| Tyler Posey | ... | Scott McCall |
| Crystal Reed | ... | Allison Argent |
| Dylan O'Brien | ... | Stiles |
| Holland Roden | ... | Lydia Martin |
| Colton Haynes | ... | Jackson / |
| Tyler Hoechlin | ... | Derek Hale |
| JR Bourne | ... | Argent |
| Linden Ashby | ... | Sheriff Stilinsky |
| Melissa Ponzio | ... | Melissa McCall |
| Jill Wagner | ... | Kate Argent |
| Keahu Kahuanui | ... | Danny |
| Adam Fristoe | ... | Mr. Harris |
| Eaddy Mays | ... | Mrs. Argent |
| Desiree Hall | ... | Jennifer |
| Adam C. Edwards | ... | Tyhurst |
| Adam Rosenberg | ... | Brian |
| Nolan Godfrey | ... | Lacrosse Player |
| Orny Adams | ... | Coach Bobby Finstock |
| Seth Gilliam |
| |
| Ian Bohen | ... | Peter Hale |
| Stephen David Calhoun | ... | Marcus |
| JayR Kalis | ... | Ulrich |
| Ian C. King | ... | High School Student |
| Jonathan Kleitman | ... | Unger |
| Carrie Kroll | ... | Mom #1.5 / ... (2 episodes, 2011) |
| Jeff Rose | ... | Mr. Martin (2 episodes, 2011) |
| Brian Bascle | ... | Janitor (1 episode, 2010-2011) |
|
| Taylor Prezzano | ... | High School Student |
| Hillary Brant | ... | High School Student |
| Justin Brown | ... | High School Student |
| Anna Enger | ... | Panicked Party-goer |
| Anthony Ennis | ... | Party Guest |
| Maggie Hollis | ... | Mom in Bowling Alley |
| Carey Jones | ... | Alpha Werewolf |
| Jennifer Juniper | ... | High School Student |
| Scottie Knollin | ... | Lacrosse Player |
| Ken Melde | ... | Bowling Alley Manager |
| Sharon Morris | ... | Mrs. Ramsey |
| Jim O'Rear | ... | Mr. Loomis |
| Robert Pralgo | ... | Mr. Whittmore |
| Lee Ramsey | ... | Party Guest |
| Cassie Smith | ... | Student |
| Albert Valladares | ... | WereWolf |
| Michael Viscusi | ... | Lacrosse Player |
| Jamie Walker | ... | Lacrosse Fan |
| Kody Wynne | ... | Video Store Clerk |
